Formulation and Evaluation of Candesartan Cilexetil 4mg Transdermal Patch

Transdermal patches containing antihypertensive drugs are preferable to conventional-dose forms because they minimize administration frequency, are less intrusive, and cause no gastrointestinal upset. Candesartan is an angiotensin-converting enzyme inhibitor that can be used alone or in combination with other drugs to treat hypertension. It may also be used as an alternative agent for the treatment of heart failure, myocardial infarction, and coronary artery disease. A transdermal patch is superior to oral administration as it avoids first past metabolism and delivers the drug for a prolonged duration. It might be the best option for the treatment and management of hypertension. The objective of this study is to develop a well-designed, stable, effective, and safe dosage form for the delivery of antihypertensive drugs.