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Recent Advances in Stem Cell Therapy for Parkinson’s Disease | Biomedgrid

Journal: American Journal of Biomedical Science & Research (Vol.7, No. 3)

Publication Date:

Authors : ; ; ; ; ;

Page : 279-291

Keywords : Parkinson’s disease (PD); Dopaminergic (DA); Embryonic stem cell (ESCs); Mesenchymal stem cell (MSCs); Neural stem cell (NSCs); Induced pluripotent stem cell (iPSCs);

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The pathologic hallmark behind Parkinson's disease (PD) is the loss of dopaminergic neurons from the substantia nigra pars compacta (SNpc) and accumulation of lewy bodies (mis-folded proteins). Clinically, in PD the patient encounter with both motor and non-motor symptoms, motor symptoms caused by loss of dopaminergic neurons from the substantia nigra, presented with tremor, bradykinesia and muscle rigidity along with impaired gait, and posture. Recent researches have enlightened the role of different type of stem cell and their clinical application. Stem cell therapy has shown promising effects on the lifestyle and behavioral changes in patients with Parkinson's disease. In this review article we will be discussing about the recent advancements in stem cell therapy for Parkinson's disease.

Last modified: 2022-06-11 16:52:56