STUDY OF HIGH RISK CASES FOR EARLY DETECTION OF CERVICAL CANCER BY PAP’S SMEAR AND VISUAL INSPECTION BY LUGOL’S IODINE METHOD.

INTRODUCTION: Cervical cancer is the commonest genital tract cancer among Indian women. Screening programmes have claimed to reduce incidence and mortality of cervical carcinoma significantly, for which sensitization of women is required through community based approach. OBJECTIVES: Comparison of VILI and cytology by PAP smear for detection of low grade squamous intraepithelial lesion, high grade squamous intraepithelial lesion, carcinoma of cervix and correlation of results with the reference standards(colposcopy and biopsy) MATERIAL & METHODS: Study was carried out in 50 women of high risk group, aged 20 to 65 years in the year of May 2008 to May 2010 in our hospital. All women were investigated with colposcopy and biopsy were taken who had abnormal colposcopy. RESULT: Sensitivity, Specificity, Positive predictive value, Negative predictive value of PAP test was 80%, 97%, 80%, 97% respectively, compared with reference standards. Sensitivity, Specificity, Positive predictive value, Negative predictive value of VILI test was 80%, 91.11%,50%,97.6% respectively, compared with reference standards. CONCLUSION: VILI and PAP test can be used effectively for detection of precancerous lesion of cervix at hospital set up as well as community level.