IMMUNOTOPIC ANOMALIES OF CONSTITUTION IN CHILDREN BORN FROM MOTHERS WITH TRANSPLANTED ORGANS AND TISSUES

Constitutional anomalies are borderline variants of the body development. The purpose is to study the constitutional features in children born to mothers with transplants, as well as to assess the immunological status of these children during the first year of life. Material and methods. The immunological status of 18 children born to mothers with transplants was studied using monoclonal antibodies by indirect immunofluorescence during the first year of life. Results. The functional immaturity of the immune system in the form of insufficiency of the immunoregulatory link of immunity was established. We identified three types of immunotopic anomalies of the constitution in children born from mothers with transplanted organs: atopic, hyperergic and hypoimmune.