“Formulation and Evaluation of Transdermal Patches”Journal: International Journal of General Medicine and Pharmacy (IJGMP) (Vol.10, No. 2)
Publication Date: 2021-08-24
Authors : Konica K. Borkar Madhur Channawar Swapnesh Chandekar Dhammadip C. Nandgaye; Pranay Moon;
Page : 51-66
Keywords : Pioglitazone; Transdermal Patches; In-Vitro Release; In Vitro Permeation Study;
The main objective of the present study was to formulate and evaluate matrix type Pioglitazone transdermal patches and to determine the drug release. Firstly, characterisation of the drug was done by performing FTIR compatibility studies and found that there was no interaction between the drug and polymers under study. Formulations (F1 to F6) were prepared using different ratios of HPMC E15 and Eudragit L 100 and penetration enhancer DMSO was incorporated to the above formulations (F7 to F12).
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