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ATP SYNTHASE AND NEUROGLIBIN CO-LOCALIZATION IN RAT BRAIN NEURONS

Journal: Journal of the Grodno State Medical University (Vol.20, No. 4)

Publication Date:

Authors : ; ;

Page : 433-439

Keywords : ATP synthase; neuroglobin; neurons; brain; rat;

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Abstract

Aim. Comparative assessment of the distribution of ATP synthase and neuroglobin in neurons of different parts of the rat brain. Material and methods. The study was performed on the material from 5 outbred male rats. Immunohistochemical, cytophotometric and statistical research methods were used. Results. ATP synthase and neuroglobin are unevenly distributed at the regional and cellular level, the ratio of the content of these proteins varies significantly. Positive medium correlation exists between contents of these two proteins in different neurons, especially in phylogenetically older parts. The ratio of proteins does not depend on neurotransmitter nature of neurons, but depends on the position of neurons in reflex arc. Conclusions. The distribution ratio of ATP synthase and neuroglobin in brain neurons is characterized by a positive correlation and that indicates spatial and functional connections.

Last modified: 2022-09-20 17:39:31