Comparative Study of Lipid Profile in Premenopausal and Postmenopausal Women

Introduction: Menopause is a natural aging process that signifies the end of reproductive years with cessation of cyclic ovarian function as manifested by cyclic menstruation. Ovaries fail completely to produce estrogen. Physical inactivity and decreased estrogen level contribute to cardiovascular disease risk in postmenopausal women. Aim and Objective: The aim of present study is to compare lipid profile in premenopausal and postmenopausal women and find out its correlation with lipid profile. Material and Methods: The lipid profile of 60 premenopausal and 60 postmenopausal women were compared. Parameters under study were height, weight, BMI, lipid profile parameters such as total cholesterol, triglyceride, HDL, LDL, VLDL. Result: We found significant increase in BMI, total cholesterol, triglyceride, LDL, VLDL and significant fall in HDL in postmenopausal women as compared to premenopausal women. Conclusion: There is increased tendency of obesity and atherogenic lipid profile in postmenopausal women as compared to premenopausal women.