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Aqueous media preparation of 2-amino-4H-benzopyran derivatives using cerium oxide nanoparticles as a recyclable catalyst

Journal: Asian Journal of Green Chemistry (Vol.6, No. 3)

Publication Date:

Authors : ; ;

Page : 194-202

Keywords : 2; Amino; 4H; benzopyran NanoCeO2 One; pot Multi; component reaction;

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2-amino-4H-benzopyran derivatives have received considerable attention due to their valuable biological and medicinal properties such as anticoagulant, antispasmodic, diuretic, and anti-cancer activities. Benzopyran derivatives have strong relaxing activity on blood vessels, cardiac muscles, and smooth muscles. The present study reports the easy synthesis of 4H-benzopyran derivatives by using aldehyde, malononitrile, and dimedone in the presence of cerium(IV) oxide nanopowder as a non-toxic catalyst. The advantages of this method include catalyst recovery, high efficiency, short reaction time, and ease of operation method.

Last modified: 2022-10-10 17:22:34