HYPOFRACTIONATED RADIATION IN THE TREATMENT OF LOCALIZED PROSTATE CANCER: LITERATURE REVIEW

Prostate cancer is responsible of a high mortality its prognosis has been improved in recent years thanks to radiotherapy (RT) which is considered the reference treatment for localized or locally advanced stages. However, spreading the RT sessions over almost two months poses problems of fatigue linked to repetitive movements, particularly for the oldest patients, but also of the overall cost of the treatment, including the time of occupation of the machine and transportation. To meet these constraints, other RT regimens have been developed seeking to maintain identical efficacy and toxicity while reducing the total duration of treatment. These so-called hypofractionated protocols use recent techniques of image-guided RT (IGRT) and conformal RT with intensity modulation (IMRT).