ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Antifungal Potential of Purified Gambier (Uncaria gambir Roxb.)

Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.8, No. 2)

Publication Date:

Authors : ; ; ; ;

Page : 40-43

Keywords : Antifungal; Uncaria gambir; Purified Gambier; Diffusion Agar Method;

Source : Downloadexternal Find it from : Google Scholarexternal

Abstract

The opportunistic Candida species that cause candidiasis are fungi that are infectious. The incidence of candidiasis has increased, due to prolonged antibiotic therapy and an increased number of immunocompromised patients. This study aimed to evaluate if Purifeid Gambier extracts have antifungal activity in vitro against Candida albicans. The antifungal activity of Purified gambir extract (Uncaria gambir Roxb.) with concentrations of 32%, 16%, and 8% was tested against Candida albicans using the agar diffusion method. Purified gambir extract at concentrations of 8%, 16%, and 32% showed antifungal activity against Candida albicans with an average inhibition zone diameter of 5.95 mm, 13.8 mm, and 15.9 mm, respectively. In conclusion, purified gambir extract (Uncaria gambir Roxb.) has strong antifungal activity against Candida albicans.

Last modified: 2023-03-20 22:26:16