ACTIVITES ANTIFONGIQUE ET ANTIBACTERIENNE DES EXTRAITS DE FEUILLES DESTYLOSANTHES ERECTABEAU

During this work, phytochemical analyzes were carried out on the powder of the leaves of Stylosanthes erecta P. Beauv., as well as qualitative analyzes by thin layer chromatography(TLC) and evaluations. The antifungal and the antibacterial activities of the aqueous extracts were made respectively by the diffusion method and by the dilution method.The TLC revealed the spots including gallic tannins, catechism tannins and flavonoids.The antifungal activity against Candida albicans is proportional to the increase in the concentration of the extracts of total tannins. Concentrations of 1000 µg/mL and 1500 µg/mL showed complete inhibition of fungal density. Maceration extracts have more antifungal activity than decoction ones. As for the antibacterial activity, Streptococcus ss and N. gonorrhea were more sensitive to thecrude and tannin extracts than flavonoids ones. The largest inhibition diameters were 15 ± 0.05 mm and 16 ± 0.04 mm on clinical strains. S. typhi was more sensitive to flavonoid extracts. The minimum inhibitory concentration was around 0.5 mg / mL on E. coli, S. typhi, Streptococcus and N. gonorrhea.