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IN-VITRO ANTI-CANCER POTENTIAL OF WHOLE PLANT OFLANTANA CAMARA EXTRACT USING HELA CELLS LINE

Journal: International Journal of Advanced Research (Vol.11, No. 03)

Publication Date:

Authors : ; ;

Page : 597-605

Keywords : Ethanolic Extract Lantana Camara MTT Assay HeLa Cells;

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Abstract

Background: The aim of this study was to examine the anticancer property of Lantana Camara on HeLacells. Material and Methods: Using ethnomedical datasubmission , the Indian medicinal plant(L.Camara) which are used in traditional medicine for cancer diseases were collected. The crude extracts was prepared by ethanolic extraction methods using standard protocols. The anticancer effects on alcoholic extracts of Lantana Camaraplants functioning a proliferation of cancerous cell lines, which are HeLa cell lines. Which make use of cytotoxicity assay, an cell viability, OD value and the IC50 of L.camarawas determined. This extracts sign influential for the treatment of cervical cancer. Results: The ethanolic extract of L.camaraexhibit good cytotoxicity for-which concentration dependent. It repose contrasting ,incase of ethanolic extracts, the cell viability was begin to increase while the concentration of extract increases. It states that not just the concentration of extract is experience the effect on cell viability, even the methods and solvents of extraction are chief in make aneffects on cell line. Conclusion: The ethanolic extract of L.camarareveal the cytotoxic effects on HeLa cells for which the plants used as anticancer herbal drugs, our outcome shows a cytotoxic activity on cancer cells.

Last modified: 2023-04-28 16:13:03