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Journal: Journal of the Grodno State Medical University (Vol.21, No. 2)

Publication Date:

Authors : ;

Page : 156-160

Keywords : cardiac surgery; surgery; phosphorus; hypophosphataemia;

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Perioperative phosphorus monitoring should be used to prevent the complications after cardiac surgery and, as a result, to reduce the length of intensive care and hospital stay. The purpose of the study was to describe the change in blood phosphorus concentrations in open heart cardiopulmonary bypass surgery patients over time. Material and methods. A prospective non-randomized cohort study was performed. The change in phosphorus concentrations was assessed in 45 adult patients admitted to the Cardiac Surgery Department for an open heart cardiopulmonary bypass surgery. All patients gave venous blood samples at the following sampling time points: 1 – before the surgery; 2 – at 24 hours after the start of the surgery, 3 and 4 – at 48 hours and 72 hours, respectively. Phosphorus concentrations were assayed by photometry at the clinical biochemistry laboratory. Results. A phase change in phosphorus concentrations was observed during the postoperative period vs. preoperative period. Blood phosphorus levels showed statistically significant increase vs. baseline by 0,193, 0,2 and 0,34 mmol/L at 24-, 48- and 72-hours post-surgery, respectively. In 33.3% of patients, hypophosphataemia of less than 0,8 mmol/L was seen at 48 hours. The change in phosphorus concentrations over time in patients with and without creatine phosphate administration was studied. Intraoperative creatine phosphate therapy did not affect the postoperative phosphorus levels. Conclusions. In the postoperative period of cardiosurgical interventions using cardiopulmonary bypass, it is necessary to control the content of phosphorus in the blood serum and, if hypophosphatemia develops, to perform the introduction of phosphates.

Last modified: 2023-05-17 16:23:57