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Sharpshooter (40%Profenofos and 4% Cypermethrin)-Induced Oxidative Stress Response in African Catfish Clarias Gariepinus |Biomedgrid

Journal: American Journal of Biomedical Science & Research (Vol.7, No. 5)

Publication Date:

Authors : ; ; ;

Page : 417-420

Keywords : Toxicity; Sharpshooter; Clarias Gariepinus; Oxidative Stress;

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This study was aimed to determine the effect of exposure of juvenile fish Clarias gariepinus (250 ± 1.2 g) to sub lethal doses (0.014 mg/L and 0.036 mg/L) of sharpshooter on the oxidative stress indices; lipid peroxidation (LPO), superoxide dismutase (SOD) and catalase (CAT) activities over a period of 15 days exposure in three replicates. The colorimetric analysis of the samples collected on day 1, 5, 10 and 15 for LPO, SOD and CAT showed different effects with time and concentration. The LPO at 0.014mg/L and 0.036mg/L were (8.69±4.002b2 - 8.390±4.426b2) and (7.275±6.567b2 - 7.275±2.00b2) showing increase with increasing concentration of pesticide compared with the control (3.030±0.00b2-1.515±2.142b2) respectively. The SOD activity increased (0.317±0.129b2-0.433±0.055b2) at 0.036 mg/L with time of exposure and decreased with concentration compared with control (0.491±0.006b2-0.053±0.005b2) respectively. CAT activity over the exposure time of 15 days showed a non - significant decrease from 0.16±0.000b2-0.013±0.00b2 at 0.014 mg/L and 0.014±0.000b2–0.011±0.00b2 at 0.036 mg/L of sharpshooter respectively compared with control (0.013±0.000b2). At days 5 and 10, sub lethal concentration of sharpshooter (0.036 mg/L) gave significant increase in LPO and decrease in SOD and CAT compared with the control respectively. The result suggests that induction of lipid peroxidation and alteration in the antioxidant enzymes (Superoxide dismutase and catalase) due to the presence of sharpshooter may cause an imbalance in the generation of free radicals and the antioxidants system in juvenile catfish especially at higher concentrations with long exposure.

Last modified: 2023-05-26 21:23:39