H2Oslim®, the water-soluble polysaccharides from Agaricus bisporus, significantly reduces body weight and improves lipid parameters in overweight humans in a randomized double-blind vs placebo study |Biomedgrid

In vitro tests demonstrated that the water-soluble polysaccharides from Agaricus bisporus is capable of trapping fat through a cationic polymer trapping net in contact with water. The fat trapping capability of this cationic net could favorably impact on blood lipid levels and diminishing cardiovascular risk factors. The aim of the study was to understand the effects of H2Oslim®, on body weight and associated metabolic parameters in overweight human volunteers. The study participants comprised of 100 healthy, overweight volunteers (defined as BMI 25-30 kg/m2) randomly divided into two groups. The groups received on a daily basis, either 400 mg of H2Oslim® or matching placebo in a double blinded. Participants were evaluated at baseline, 4, 8 and 12 weeks of the study. Significant improvements in body weight, waist circumference as well as plasma total cholesterol, LDL cholesterol, were observed in the H2Oslim® group (H-group) compared with the placebo group (P-group). The results here reported revealed that the supplementation of H2Oslim® seems a useful tool in dealing with obesity and hyperlipidemia.