Comparative Study of Different Brands of Ranitidine Available in India

It can be challenging to choose the safest, most cost-effective, and effective brand of ranitidine because it is used to treat peptic ulcers and is marketed under numerous names. The purpose of this study is to determine whether the various brands of ranitidine HC pills sold in Karachi, Pakistan, are comparable to one another. For the study, four different brands of (150 mg) were used. Six quality control measures were carried out according to USP specifications, including weight variation test, hardness test, thickness test, friability disintegration test, and dissolving test. In terms of hardness, weight fluctuation, thickness friability, disintegration, and dissolution, the results showed that all brands are within tolerances. All brands' disintegration times were under 15 minutes, which was commendable according to the USP. Within 45, all brands displayed Q values more than 80%.