Epigenetic Role of Noncoding RNAs in the Recurrence of Pituitary Adenoma after Surgical Resection |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.10, No. 4)Publication Date: 2020-09-25
Authors : Ji Eun Park; Hoon Gi Kim; Jinuk Kim; Gyuseo Jung; Geun Young Yang; Young Zoon Kim;
Page : 364-374
Keywords : Non-functioning pituitary adenoma; Recurrence; Protein-coding genes; Long noncoding RNAs; Therapeutic;
Abstract
Background: Due to the lack of related symptoms and the hypersecretion of serum hormones, it is difficult to monitor and predict the postoperative recurrence of non-functioning pituitary adenomas (NFPAs). Long noncoding RNAs (lncRNAs) and protein-coding genes (PCGs) play critical roles in the development and progression of many tumors. However, the complex network of RNA interactions related to the mechanism and function of the postoperative recurrence of NFPA is still unclear.
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