Toxic Epidermal Necrolysis A Case Report

Toxic Epidermal Necrolysis TEN is a rare but serious dermatological emergency characterized by diffuse exfoliation of the skin and mucous membranes due to immune mediated destruction of the epidermis which can lead to sepsis and respiratory distress. Early diagnosis and aggressive medical care is essential for the reduction of high morbidity and mortality associated with this disease. Toxic epidermal necrolysis TEN is a rare, acute, severe mucocutaneous reaction commonly presenting following medication use antiepileptic drugs, Corticosteroids, Antiretroviral drugs abacavir and nevirapine, Antibiotics, Allopurinol, NSAIDs non steroidal anti inflammatory drugs . A 20 year old girl presented with altered sensorium, fever, generalized erythematous skin rashes and facial puffiness she is under ant tubercular therapy, corticosteroids and phenytoin, characteristics of Toxic Epidural Necrolysis. Dr. Mary Minolin T | Padmavathi M "Toxic Epidermal Necrolysis: A Case Report" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-1 , February 2023, URL: https://www.ijtsrd.com/papers/ijtsrd53869.pdf Paper URL: https://www.ijtsrd.com/medicine/other/53869/toxic-epidermal-necrolysis-a-case-report/dr-mary-minolin-t