Early and Late Brain Toxicity after Prophylactic and Curative Whole-Brain Radiotherapy with or without Re-irradiation |Biomedgrid

Brain metastases (BM) are the most frequent intracranial neoplasms in adults. Due to the development of the imaging diagnosis and the efficacy of complex oncology treatment, there is a significantly increased overall survival of patients with malignancies. On this background, clinical cases with brain metastases are also with increasing frequency. In addition to surgery, their treatment involves the application of various radiotherapeutic techniques with different radiation volumes and fractionation of the radiation dose. We present four clinical cases with early and late neurotoxicity after radiotherapy (RT) on the prevention or treatment of brain recurrences or metastases.