The Antibacterial and Antiuroletiasis Activities of Cissus Rotandifolia Extract on Urolithiasis Rats Induced by Ethylene Glycol and its Mechanism as Antiurolithiasis Remedy |Biomedgrid

Cissus rotandifolia (CR) is a medicinal plant widely used in the southern region of Saudi Arabia and Yemen. The present study aimed to evaluate the antibacterial and antiurolithiasis effect of CR and its mechanism. Thirty rats divided into five groups: Group A (negative control), Group B were treated with EG and ammonium chloride (AC) and served as positive group. Group C and D served as treated groups and treated as B group with 200 mg/kg and 400 mg/kg of CR respectively for 28 days and group E fed as group B for 28 days and then treated for28 days by 1000 mg CR extract and served as curative group. Another 10 rats divided into two groups: group F took normal diet and served as negative control group and group G took normal diet with 500 mg/kg of CR to investigate the mechanism of CR as antiurolithiatic substance.