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The Incidence Side Effects of Antihypertensive Drugs in the Intensive Care Unit General Hospital Dr.M.Ddjamil Padang

Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.9, No. 2)

Publication Date:

Authors : ; ; ; ;

Page : 29-35

Keywords : antihypertensive drug; side effect; Naranjo;

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To lower morbidity and mortality from disease complications, the goal of hypertension treatment is to maintain target blood pressure. The management of hypertension necessitates lifelong medication, which carries the risk of adverse drug reactions. This study attempts to ascertain the occurrence of antihypertensive drug side effects and the description of antihypertensive drug use in Dr. M. Djamil Padang Hospital's Intensive Care Unit based on the Naranjo algorithm. Using cross-sectional methodology and retrospective data, this study is an example of non-experimental descriptive research. 60 patients met the inclusion criteria according to the study's findings. The most utilized medicines were those in the Calcium channel blocker (CCB) class. The incidence of side effects was found to be 18 patients (55 different types of pharmaceuticals) in the moderately likely category and 1 patient (2 different types of drugs) in the uncertain category based on the Naranjo algorithm. The side effects that caused more than 10% were edema (12.28%), hypotension (38%), cough (15.78%), and hyponatremia (14.03%). Chest pain (8.77%), shortness of breath (5.26%), nausea, and vomiting (5.26%) were the side effects that manifested <10%. Antihypertensive medication side effects remain in the Central General Hospital (RSUP), Dr. M. Djamil Padang's Intensive Care Unit (ICU).

Last modified: 2024-02-17 00:54:08