AN OVERVIEW ON THERAPEUTIC SCREENING USING EXPERIMENTAL MODELS OF WOUND HEALING

The complex process of wound healing is how damaged tissue heals itself. It's a process that includes homeostasis, tissue integrity coordination, and the activation of intercellular pathways. The present review was based on the therapeutic screening using experimental models of wound healing. Hemostasis and clot formation are the two main complicated events that take place during this phase. The clot has aggregated platelets encased in a fibrin network. Oxygen is necessary for almost all wound-healing processes and cell metabolism, particularly to produce energy via ATP. It stops wounds from getting infected, stimulates the growth of new blood vessels, raises the differentiation, migration, and re-epithelialization of keratinocytes, boosts the production of collagen and fibroblasts, and encourages wound contraction. Wound healing models include incision, excision and burn model. In conclusion, our understanding of wound pathophysiology will be significantly advanced by combining these strategies with cutting-edge tissue, cell, and molecular "omics" technology. Developing novel therapeutic approaches for enhanced wound care is, in fact, one of the many promising areas of the future.