Demographic, Comorbidity, and Antibiotic Patterns in Osteoarthritis Patients Undergoing Knee and Hip Replacement

This study focuses on the evaluation of antibiotic therapy in preoperative and postoperative conditions of Total Knee Arthroplasty (TKA) or Total Hip Arthroplasty (THR) in patients with osteoarthritis. The analysis of data from the study reveals that osteoarthritis predominantly affects individuals above 45 years, with an increased incidence after the age of 55. Females represent 64.3% of diagnosed patients, indicating a higher predisposition in women. Primary complaints include knee and hip pain, difficulty in walking, stiffness, and swelling, with walking difficulty and stiffness being prominent. Patients with osteoarthritis commonly exhibit comorbidities, with hypertension and diabetes being prevalent, alongside other conditions such as heart, thyroid, and kidney-related disorders. Among osteoarthritis patients, 71.4% required Total Knee Replacement (TKR), while 28.6% required Total Hip Replacement (THR). Female patients comprised a higher percentage for both TKR (65%) and THR (62.5%). Antibiotic administration pre-surgery primarily involved Inj. Cefuroxime (1.5gm) or Inj. Amikacin (500mg), with 37.5% receiving both. Similarly, during surgery, 64.3% of patients received both antibiotics. Post-surgery antibiotic regimens mirrored the pre-surgery administration. This data provides valuable insights into the demographic distribution, comorbidities, surgical requirements, and antibiotic usage patterns in osteoarthritis patients undergoing TKR and THR surgeries. The findings contribute to a comprehensive understanding for future research and clinical interventions, aiming to enhance patient care and optimize treatment strategies in orthopedic procedures.