The inert surface contamination of SARS-CoV-2 and the effect of disinfectants in one of the specialized and main responsible hospitals for COVID-19 patients in Ahvaz, Iran

Background: SARS-CoV-2, the causative agent of the COVID-19 pandemic, spreads through both direct and indirect pathways. Among the latter, surface contamination is a significant concern due to the virus's prolonged viability on surfaces. There is ongoing discussion over the impact of environmental surface contamination, especially in light of the introduction of novel viral types. The present study aimed to examine the extent of environmental surface contamination across different hospital wards and evaluate the effectiveness of disinfectants in inactivating the virus. Methods: The samples were collected from critical areas in a hospital, both pre-disinfection (n = 40) and post-disinfection (n = 17), using reverse transcription-polymerase chain reaction (RT-PCR) to detect SARS-CoV-2. Results: The findings indisputably confirm the presence of SARS-CoV-2 on swab samples from frequently-touched surfaces. Notably, 10 samples were virus-positive before disinfection, highlighting persistent viral contamination in vital hospital zones. Conclusion: This study underscores the critical role of environmental surface contamination in SARSCoV- 2 transmission, particularly in healthcare settings. Detecting the virus on frequently-handled surfaces underscores the urgent need for rigorous and frequent surface disinfection. Effective surface disinfection remains a rapid, straightforward, and practical strategy to mitigate virus transmission to healthcare workers and patients. These findings hold significant implications for infection control, particularly amid emerging virus variants. They emphasize the need to maintain stringent hygiene and disinfection practices within healthcare facilities to combat the spread of COVID-19.