Is the Innate Immune Response Involved in the Transient Protection Provided by Spike-Based COVID-19 Vaccines? |Biomedgrid

Recently, some regional and/or national governments have suggested the need of three-monthly application of COVID-19 vaccines to keep optimal protection. This suggestion is given mainly by the now clear waning immunity that has been observed with SARS CoV-2 Spike-based vaccines, believed to be responsible for outbreaks in countries with >70% vaccinated population and supported by several studies from different countries [1].