Formulation and Evaluation of Herbal Chewing Gum |Biomedgrid

Chewing gum is a mobile drug delivery system. It is potentially use for administrating drugs either locally or systematically via, the oral cavity. Herbal chewing gum has through the year gained increased acceptance as a drug delivery system. Several ingredients are now incorporated in herbal chewing gum. The aim of this study was to formulate herbal chewing gum using cinnamon oil and to prove its antibacterial property effectively at low dosage. Because cinnamon oil is a greater antibacterial agent against the Streptococcus mutans that causes tooth decay. The herbal chewing gum of cinnamon oil is prepared using different concentrations of cinnamon oil and yastimadhu. The prepared chewing is evaluated for different parameters like color, stickiness, weight variation, hardness, and in vitro drug release. In vitro drug release was performed by modification dissolution apparatus. It was seen that in formulation f2 drug release was increased compared to formulation f1 and f3. The formulation shows maximum drug release of 93% in 14 min. compared to all other formulations. So, chewing gum is used in the treatment of local disease in the oral cavity.