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BREXPIPRAZOLE AUGMENTATION ON MIRTAZAPINE FOR TREATMENT-RESISTANT DEPRESSION IN AN ELDERLY PATIENT

Journal: International Journal of Advanced Research (Vol.13, No. 05)

Publication Date:

Authors : ; ;

Page : 1300-1303

Keywords : ;

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Abstract

Treatment-resistant depression (TRD) poses a significant clinical challenge, particularly in elderly patients, due to age-related physiological changes, comorbidities, and reduced medication tolerability. TRD is generally defined as a major depressive disorder (MDD) that fails to respond to at least two adequate antidepressant trials.

Last modified: 2025-06-19 16:30:33