Screening of Antibacterial Activity of Cissus Quadrangularis and Boerhavia diffusa against Clinical Pathogens

Medicinal plants available locally in nature are now in eradication. Many plants used in traditional medicine represent rich sources of natural bioactive substances with health promoting effects and no side effects. The use of modern medicines is developing. Even though it is necessary, the medicinal plants and it uses should be protected. Researches should be conducted on medicinal plants to develop medicines. The chief significance of the below study was to test antibacterial activity of methanol and ethanol extracts of Cissus quadrangularis and Boerhavia diffusa against clinical pathogens. The leaves of Cissus quadrangularis and Boerhavia diffusa were collected from Kattumannarkoil village, Cuddalore district, Tamilnadu. The methanol and ethanol extracts of dried leaves were prepared. The methanol and ethanol extracts were tested for antibacterial activity against Escherchiacoli, Staphylococcus aureus, Klebsiella and Pseudomonas in different concentrations. The ethanolic extract of Cissus quadrangularis showed manimum zone of inhibition (21?0.3mm) against Klebsiella in the concentration of 150 ?l. The minimum antibacterial activity exhibited by Boerhavia diffusa against tested clinical pathogens. In this present study Cissus quadrangularis showed maximum antibacterial activity. The extract of this plant leaves can be used to replace chemical antibiotics.