Clinical Profile of Systemic Lupus Erythematosus in Tertiary Care Centre

Prevalence of SLE is 3.2/100, 000 population in India4.SLE is more common in females, especially in childbearing age as compared to males with a ratio ranging from 7:1 to 15:15 due to role of estrogen. Very few studies conducted in Maharashtra regarding study of clinical profile of systemic lupus erythematous in tertiary care center. So we are interested to find out the various risk factors of SLE, clinical profile, incidence of various SLE manifestations and complications. We are interested to study association and impact of risk factors. This disease is studied extensively in western world (over 65000 articles are there in Pub med) but not studied so well in Maharashtra. Regional variation has been observed regarding renal involvement in SLE patients ranging from 20% to 73%. Studies conducted from the northern 4 and western India 7 has shown higher prevalence of renal involvement as compared with south India. 8, 2 Methods: It is a prospective observational study carried out in tertiary care centre from October 2019 to December 2021. Conclusion: The majority of research participants were between the ages of 12 and 30. Majority of study participants were Females. Most common Hematological manifestations was Anaemia. Most common musculoskeletal manifestation was Polyarthritis. Photosensitivity was the most common Mucocutaneous manifestation. Most common neurological features found in patients were depression. Pericardial effusion was most common cardiovascular manifestations. Proteinuria was most common Renal features. Ascites was common gastrointestinal manifestation. In cases of renal failure, l the majority of fatalities was caused by sepsis.