The Effects of Varicocele on DNA Morphology

Infertility is defined as a failure to achieve pregnancy in spite of regular unprotected sex. The male infertility by 50% contributes to this important health problem affecting about 15-20% of couples in society [1,2]. A study carried out by the World Health Organization (WHO) in1992, which included 9,034 infertile couples, indicated varicocele in 25.4% of men with disordered sperm parameters and in 11.7% of men with normal sperm parameters [3]. Varicocele is the dilatation of the pampiniform plexus veins within the spermatic cord [4]. Varicocele occurs in roughly 15% of the adult male population. The rate of occurrence increases to 21-41% in men with primary infertility and to approximately 80% in those with secondary infertility [5,6]. Varicocele is found on the left side of the scrotum in 75-95% of cases. While its bilateral likelihood is 10%, the likelihood of varicocele occurring on the right side of the scrotum is 2%.