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Staphylococcal scalded skin syndrome ? A case series with review of literature

Journal: International Archives of Integrated Medicine (IAIM) (Vol.2, No. 6)

Publication Date:

Authors : ;

Page : 214-219

Keywords : Staphylococcal scalded skin syndrome; Staphylococcus aureus; Exfoliative toxins; Desmoglein-1; Nikolsky’s sign.;

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Staphylococcal scalded skin syndrome (SSSS) is an acute dermatological illness which requires prompt treatment. It is a condition associated with widespread exfoliation of skin caused by Staphylococcus aureus (SA). The toxins elaborated by these gram positive microorganisms especially the exfoliative toxins A and B causes the SSSS. Literature review mentions that only 5% of SA produces these exfoliative toxins. The main route of spread of the toxins is by the hematogenous spread and the process results in extensive damage to the epidermis. This case series reports the SSSS in two children and highlights the significance of promptly diagnosing this serious pediatric dermatological illness.

Last modified: 2015-06-25 18:21:39