MANAGEMENT OF A NTI - TUBERCULAR THERAPY IN DUCED HEPATITIS AND TUBERCULOUS MENINGITIS COMPLIC ATIONS IN A YOUNG ADULT PATIENT: A CASE REPORT Kandimalla. Chaitanya * , Bandlamudi. Yasaswini, Sudhakar R, Minu K George

Tuberculous Meningitis (TBM) is the most dr eaded form of tuberculosis (TB) with Central Nervous system involvement which has very high morbidity and mortality rate. It is noted in 5 to 10% of extra pulmonary TB cases, and accounts for approximately 1% of all Tuberculosis cases. Multi - drug regimen i ncludes Isoniazid, Rifampin, Ethambutol, Pyrazinamide and Streptomycin along with adjunctive treatment with corticosteroids is required in the effective management of Tuberculosis meningitis. Anti - Tuberculosis Therapy induced Hepatotoxicity is the well - kno wn side effect of several drugs which are used for the treatment of TB and it is found to be 2% to 28%. We report a case of ATT induced hepatitis (Isoniazid - Rifampin) along with tuberculosis meningitis complications such as grade II Obstructive Hydrocephal us and hyponatremia and it is successful management with Inj.Mannitol and Inj.Dexamethasone. Key Words: Tuberculous Meningitis, ATT induced Hepatitis, Hydrocephalus, Hyponatremia