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Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.2, No. 10)

Publication Date:

Authors : ; ; ; ;

Page : 1399-1407

Keywords : Preformulation; dissolution; oxiadation; computability studies;

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Every drug has intrinsic chemical and physical properties which has been consider beforedevelopment of pharmaceutical formulation. This property provides the framework for drug’scombination with pharmaceutical ingredients.Preformulation studies carried out by various research scientists is reviewed. Preformulationstudies conduct for newly synthesiedcompounds or extracted compound and it gives the information regarding the degradation process, any adverse conditions relevant to the drug, bioavailability, pharmacokinetics and formulation of similar compound and toxicity. Preformulation studies strengthen the scientific foundation of the guidance, provide regulatory relief and conserve resources in the drug development and evaluation process, improve public safety standards, enhance product qualityin the fabrication of dosage form. Key words: Preformulation, dissolution, oxiadation, computability studies

Last modified: 2015-11-07 13:34:55