PATHOCHEMICAL EFFECTS OF INTERMITTENT ALCOHOL INTOXICATION IN RATS

The article provides the analysis of biochemical changes in the blood plasma and tissues of rats at two different modes of intermittent alcohol intoxication (DAI-4 and DAI-7). During DAI-4 the levels of glucose, diene conjugates, malonic dialdehyde are increased, while urea and creatinine are lowered in blood plasma. DAI-7 is accompanied by hyperglycemia and increased concentration of lipid peroxidation products. The structure of the free amino acids pool in DAI largely changes in the heart and skeletal muscles rather than in blood and liver.