Strengthening the LIPID PEROXIDATION AND SERUM ALBUMIN compensatory reactions in patients in the recovery period STROKEJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.11, No. 1)
Publication Date: 2010-02-28
Authors : Uzbekov M.G.; Alferova V.V.; Misionzhnik E. Yu.; Lukyanyuk E.V.; Hecht A.B.; Shklovskii V.A.;
Page : 49-55
Keywords : ;
Studied the concentration of malondialdehyde (MDA), an effective (ECA) and total (OCA), the concentration of CA in 30 patients (cf. the age of 69 ± 8 years, 18 women, 12 men) and 17 healthy subjects of comparable age and sex. In 88% of patients with AI showed an increase in MDA compared with the norm (P <0.01). The aim - to define the pathogenetic aspects of the processes of lipid peroxidation (LPO) in blood plasma and functional activity of human serum albumin (SA) patients in the recovery period (4-5 months) ischemic hemispheric stroke (AI). In patients with ischemic activation of LPO pathogenetically associated with a decrease in acceptor ability of the CA. Reduction ECA noted in 80% of patients with ischemic compared with normal (P <0,01). Thus, the recovery period, the AI increased lipid peroxidation is a violation of the functional activity of the CA, which is accompanied by a decrease in compensatory reaction SA.
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