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ROLE OF MECHANISMS OF VIOLATIONS proliferation and apoptosis in morphogenesis fibrocystic disease of breast

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.12, No. 1)

Publication Date:

Authors : ;

Page : 146-153

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In this paper, an analysis of published data shows the significant role of apoptosis during ontogenesis of the breast, the neoplastic transformation of tissues and the likely importance of these processes in the mechanism of hyperplastic processes and fibrocystic disease of breast cancer. However, it remains unresolved the question of what biological markers may serve as quantitative indicators of proliferative activity of breast tissue, as well as objectively reflect the severity of apoptosis and the activity of genes - tumor suppressor. Studying the expression of molecules of products of genes-regulators of cell proliferation and apoptosis is of great scientific interest because it can probably afford to hold detalizovannye risk assessment for breast cancer, followed by the prediction of the disease

Last modified: 2016-03-26 01:07:18