ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Profile of SCCmec types in clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) in a hospital in Southern Brazil

Journal: Journal of Health and Biological Sciences (Vol.4, No. 1)

Publication Date:

Authors : ; ;

Page : 5-7

Keywords : Methicillin-Resistant Staphylococcus aureus. Molecular Typing. Polymerase Chain Reaction;

Source : Downloadexternal Find it from : Google Scholarexternal


Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen that affects public health representing the most common infections related to health care and community. MRSA infections are classified as health care-associated MRSA (HA-MRSA) and community-associated MRSA (CA-MRSA) defined by the bacteria genetic profile. Objective: This study conducts a molecular characterization of MRSA isolates from a hospital in Porto Alegre, RS, Brazil, in order to determine the profile of SCCmec types. Methods: Eighty-one MRSA isolates from a hospital in Porto Alegre, RS, Brazil, collected from January to June of 2012 were included in the study. A multiplex PCR was performed to determine the SCCmec types. Results: From the 81 isolates, 24 (30%) were type I, 10 (12%) type II, 21 (26%) type III, 4 (5%) type IVa, 12 (15%) isolates were type IVc, 1 isolate was type I and IVc (1%) and 1 was type III and IVc (1%) simultaneously, while non-typable isolates corresponded to 8 isolates (10%). Conclusion: However most of the isolates were carrying SCCmec types related to HA-MRSA; the results reveal a change in the epidemiology, considering the decrease of the incidence of SCCmec type III and the increase of isolates being typed as SCCmec I.

Last modified: 2016-04-01 07:08:05