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Hepatic cholangiocarcinoma in a feline and anatomopathologic and clinical findings, compatible with Feline Infectious Peritonitis

Journal: REVISTA MVZ CÓRDOBA (Vol.17, No. 2)

Publication Date:

Authors : ; ; ;

Page : 3080-3086

Keywords : Cholangiocarcinoma; cats; dehydration; bile ducts;

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Path morphological findings are presented regarding hepatic cholangiocarcinoma (CGC) with peritoneal effusion in a elderly domestic cat; its relation with clinical symptoms and pathological findings consistent with feline infectious peritonitis (FIP). The veterinary clinic of the Universidad de los Llanos dealt with a feline patient 8 years old, criollo, with increased abdominal silhouette and depression. 7% dehydration, hypothermia (37.2°C), pale mucous membranes, dyspnea and hepatomegaly were determined clinically. A performed abdominocentesis presented nonseptic exudate and a cytological symptom consistent with CGC with low columnar cells arranged in a honeycomb structure, presenting anisokaryosis, moderate hipercromacia, clear cytoplasm and accompanied by a dirty inflammatory and hemorrhagic background with cellular debris. The radiographic analysis showed hepatomegaly with a dotted pattern characteristic of neoplastic and ascite formations. A necropsy showed hemothorax and hydropericardium, ascites and white solid neoplastic nodules in 45% of the liver parenchyma and nodular pattern on the visceral surface of the stomach, small, large and mesentery intestine. Samples were placed in 10% buffered formalin, processed by routine methods for optic microscopy. In relation to histopathology moderately differentiated CGC was diagnosed with intense desmoplasia. A hepatic CGC was evidenced Cytologicly as well as histopathológicly with peritoneal effusion that was associated with clinical symptoms and anatomopathological findings consistent with FIP.

Last modified: 2016-07-12 01:51:41