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The Impact of Zidovudine (An Antiretroviral Drug) on Some Serum and Erythrocyte Biochemical Parameters in Wistar Albino Rats
Journal: International Journal of Science and Research (IJSR) (Vol.2, No. 9)Publication Date: 2013-09-15
Authors : Okonkwo C.O; Uwakwe A.A.;
Page : 185-189
Keywords : zidovudine; nucleoside analog; reverse transcriptase; inhibitor; antiretroviral;
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Abstract
Zidovudine (AZT) is a nucleoside analog, a reverse transcriptase inhibitor (NRTI) and a type of antiretroviral drug used for the treatment of HIV/AIDS. The administration of zidovudine to the wistar albino rats showed an increase in erythrocyte fragility as can be seen from figure 1. There were significant (p0.05) decrease in serum ALP activity, significant (p
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Last modified: 2013-10-01 22:57:20