Different Phenotypes at Possibly Shared Genotype of Migraine Family

In this paper we described clinical features of a family including mother and all three children with migraine. Migraine is regarded as a chronic disorder with episodic manifestations and also is progressive for at least some of the patients. Our nuclear family consist mother and her all-three children with migraine. We pointed clinical differences and comorbidity of migraine with aura (MwA) and migraine without aura (MwoA) and existence of cutaneous allodynia (CA) at this family. We believe in that family or twin studies could help us not only to reveal pathophysiology of migraine but also could contribute us to understand possible effects of clinical variables (such as aura, cutaneous allodynia).