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Sex hormones alter the effect of aspirin on bleeding

Journal: International Journal of Basic & Clinical Pharmacology (Vol.2, No. 5)

Publication Date:

Authors : ;

Page : 537-540

Keywords : Sex hormones; Aspirin; Bleeding time;

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Background: Interaction of aspirin and sex hormones was investigated through bleeding time. Methods: Bleeding time in 32 males and 105 unmarried females with previous 6 normal menstrual cycles and all aged between 18 to 21 years was found by Duke’s method before and after 2 hours of aspirin administration. Phase of menstrual cycle of each female was determined by present menstrual history. Results: Bleeding time in 32 male was 69.33± 4.94 seconds and in 105 female was 73.03±1.89 seconds which were not statistically different (P>0.05).This time was increased to 107.66±4.76 seconds in males and 113.65±3.73 seconds in females after aspirin administration which were statistically different (P

Last modified: 2013-10-17 10:42:34