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ALK POSITIVE PRIMARY EXTRANODAL ANAPLASTIC LARGE CELL LYM PHOMAMASQUERADING AS A SOFT TISSUE SARCOMA A CASE REPORT

Journal: University Journal of Pre and Paraclinical Sciences (Vol.2, No. 3)

Publication Date:

Authors : ;

Page : 131-135

Keywords : Anaplastic Large Cell Lymphoma; ALK positive; extranodal; sarcoma;

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Abstract

Anaplastic Large Cell Lymphoma (ALCL) is a rare type of T-cell null cell Non Hodgkin Lymphoma. It is seen predominantly in children and young adults. Some of these tumors express an enzyme called Anaplastic Lymphoma Kinase (ALK) produced by the alk gene, an oncogene. The disease can present purely nodally or with extranodal involvement. Extranodal involvement can mimic a soft tissue sarcoma. Purely extranodal presentation is very rare and most of these are ALK-ve ALCL than ALKpositive ALCL. We present a case of a primary extranodal ALK positive Anaplastic Large Cell Lymphoma that presented clinically as a soft tissue sarcoma in a 56-year-old female

Last modified: 2016-08-23 16:06:01