ANTIBACTERIAL OF CASSIA ACUTIFOLIA EXTRACT AGAINST SOME BACTERIA AND ANTI-BIOFILM FORMATION ACTIVITIES AGAINST PSEUDOMONAS AERUGINOSA

The present study was carried out to determine the potential antibacterial effect of Cassia Acutifolia ethanolic extract against Staphylococcus aureus, Escherichia coli and Pseudomonas Aeruginosa using the agar diffusion technique. All microorganisms showed the minimum inhibitory concentrations were investigated to characterize the antimicrobial activities of this extract. The result showed that the least MIC value of alcoholic extract of Cassia Acutifolia was 1.25mg/ml against S. aureus and 20 mg/ml againstE. Coli and P. aeruginosa whereas the highest MBC value of alcoholic extract of Cassia Acutifolia was 50mg/ml againstE. Coli and P. aeruginosa and 5mg/ml for S. aureus. The biofilm inhibitory concentration of the Cassia Acutifolia extract was 1.034-0.418mg/ml against P. aeruginosa in different plant concentration started with 50 mg/ml to 5mg/ml.