Advancement of Fluorescent Methods for Detection of Nitric Oxide

Biologically Nitric Oxide (NO) is an important inorganic compound involved in numerous signaling pathways, which has promoted the demand for analytical methods for detection of NO. Fluorescent sensing, more effective than any other detection methods, enables monitoring NO in physiological environments such as cell and blood. Fluorescent probes based detection methods have wide applications in selective and sensitive monitoring of NO production in vivo. In this review, we highlight the novel fluorescent NO sensors developed in recent years, including fabrication, analytical characteristics and biological applications.