A Case of Wegener Granulomatosis with Unprecedented Hypopharyngeal and Splenic Involvement

Wegener's granulomatosis (WG) is a rare form of necrotizing vasculitis which can affect any part of the body. We present a unique case of WG in a 22-year-old male who presented with high grade fever, ear pain, loss of weight and appetite. On subsequent investigation he was found to have multisystem involvement with uncommon ulcerated hypopharyngeal lesion and a large splenic infarct secondary to vasculitis involving the small to medium size vessels. The initial illness and one subsequent exacerbation were treated with oral cyclophosphamide and prednisone. Secondary infections have been managed with use of appropriate antibiotics.