DRUG INDUCED MEMBRANOUS NEPHROPATHY

Membranous Nephropathy (MGN) could be either idiopathic (primary) or secondary to systemic autoimmune disease, chronic infections, malignancy or therapeutic drugs. We present a 24 year old Asian lady, diagnosed to have Wilsons disease and started on D-Penicillamine. Eighteen months later she presented with nephrotic proteinuria, benign urinary sediment, normal blood pressure and normal serum creatinine. A renal biopsy was done which revealed Membranous Nephropathy. The serum M type Phospholipase A2 receptor antibody was negative.Though D-Penicillamine induced MGN is a well known entity, we are reporting this case because of its rarity