NEUROENDOCRINE TUMORS IN DECOMPENSATED LIVER DISEASE

We report two cases of neuroendocrine tumors in patients with decompensated chronic liver disease. Neuroendocrine tumour in the setting of decompensated liver disease is a very rare entity thus the presentation. Patients who had decompensated chronic liver disease, diagnosed by clinical, laboratory and imaging criteria underwent upper gastrointestinal endoscopy. During endoscopy, polyps numbering one to numerous were found in the stomach and duodenum. Biopsy was taken from polyps and sent for histopathological examination. Histopathological examination was suggestive of neuroendocrine tumor. To confirm the diagnosis, Immunohistochemistry for neuroendocrine markers, chromogranin A, synaptophysin, Leu7, and neuronspecific enolase was done. After confirmation with positive immunohistochemistry, metastatic work-up was done using CECT abdomen and PET CT scan