AN UNUSUAL PRESENTATION OF COMPLEX RENAL CYST

Renal cell carcinoma is the most common neoplasm of the kidney. It is a heterogeneousdisease, comprised of different histological variants with a distinct clinical course, genetics andresponse to treatment. The various subtypes identified include clear cell, papillary and chromophobe,among others. Chromophobe renal cell carcinoma is a rare variant and accounts for 5 of all cases.The coexistence of different subtypes of renal cell carcinoma (RCC) within a single kidney is anextremely unusual entity. Presented herein is the case of a 60-year-old woman with RCC ofchromophobe and papillary histology. Very few reports in the literature describe double or triplesynchronous renal neoplasms. To our knowledge this is the second report of this RCC subtypecombination, which might trigger further investigation on the RCC pathogenesis theories. This patientunderwent partial nephrectomy and on followup was found to be free of metastasis or localrecurrence.