Review of Inflammation and Infection in Contact Lens Wearers: Risk Factors and Association with Single Nucleotide Polymorphisms

Inflammatory corneal complications associated with contact lens (CL) wear range from self limiting sterile corneal infiltrative conditions such as infiltrative keratitis (IK), and contact lens-induced acute red eye (CLARE) to severe sight threatening microbial keratitis [1-3]. In practice, managing complications associated with CL wear has been a challenge to practitioners, especially in diagnosing and treating cases such as early microbial keratitis [1]. In addition, selflimiting conditions such as CLARE and IK can cause temporary discomfort to the wearer, and may lead to the discontinuation of CL wear.