PULSE PRESSURE CLASSES AND HEMODYNAMIC PARAMETERS IN PATIENTS AT THE ANNUAL STAGE AFTER CARDIAC RESYNCHRONIZATION AND MEDICAL THERAPY

The changes of functional blood circulation parameters in 19 patients (13 men and 6 women) at the annual stage after cardiac resynchronization (CRT) and drug therapy in pulse pressure classes (PP: I - very low PP - less than 20 mm Hg; II ? low PP ? from 20 to 40 mm Hg; III ? normal PP ? from 40 to 60 mm Hg; IV ? high PP ? from 60 to 80 mm Hg; V ? very high ? more than 80 mm Hg) were studied. The probability of differences between groups was determined with a Mann-Whitney U-test. Normalization of diastolic blood pressure (DBP), heart rate (HR) and left ventricular ejection fraction (LV EF) in all PP classes, systolic BP (SBP), end-systolic, end-diastolic volumes (ESV, EDV) in the III PP class patients at the annual stage after CRT and drug therapy were showed. The tendency of normalization of SBP in the IV class, posterior wall thickness of LV (PWLV), myocardial mass of LV (MMLV) and no change in interventricular septum thickness (IVS), left and right atrium (LA and RA), right ventricular (RV) sizes in all PP classes indicated the need for more active monitoring, careful selection of stimulation parameters and medical support correction of patients in IV PP class.